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Category: Research

Burt Nabors, M.D.
June 13, 2024

Encouraging Phase 1 data for glioblastoma treatment reported by UAB researchers at ASCO

Preliminary clinical data for glioblastoma multiforme patients enrolled in a Phase 1 clinical trial at the University of Alabama at Birmingham demonstrated that 92 percent of evaluable patients treated with INB-200 exceeded a median progression-free survival of seven months with concomitant temozolomide chemotherapy.
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Physician talking with patient
May 23, 2024

UAB is already a national leader in clinical trials. Here is how it plans to extend the benefits to even more Alabamians.

Over the past decade, the University of Alabama at Birmingham has become a national leader in clinical trials — studies examining the use of new treatments in people. And more patients than ever in Alabama have access to life-changing therapies at UAB.
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Dr. Qasim Hussaini, M.D.
April 4, 2024

New study shows association of historical housing discrimination and shortfalls in colon cancer treatment

A nationwide study of 196 cities shows that housing discrimination from 90 years ago still casts a historical shadow of inequities in colon cancer care today, S.M. Qasim Hussaini, M.D., of the University of Alabama at Birmingham and colleagues at the American Cancer Society and Johns Hopkins School of Public Health report in the journal JCO Oncology Practice.
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Illustration of medical professional giving a presentation
February 23, 2024

State of the Science Summit coming in May

Mark your calendars for this year's State of the Science Summit: Hematologic Malignancies coming to Birmingham on May 23, 2024.
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Isabel Scarinci, Ph.D., MPH
February 15, 2024

Scarinci selected to lead national cervical cancer elimination workgroup

The University of Alabama at Birmingham’s Isabel Scarinci, Ph.D., vice chair for Global and Rural Health in the Department of Obstetrics and Gynecology, was chosen to lead a workgroup charged with creating the United States cervical cancer elimination plan.  
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Two puzzle pieces coming together in collaboration
February 6, 2024

The Synergy of Collaborative Cancer Research

When members of the O’Neal Comprehensive Cancer Center investigate complex questions together, the new therapies, discoveries and patient care improvements that result become more than the sum of the parts
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February 1, 2024

BCRFA funds cancer-related research grant through O’Neal Invests

The O’Neal Comprehensive Cancer Center at UAB is pleased to announce that the Breast Cancer Research Foundation of Alabama (BCRFA) has generously funded three Pre-R01 grants through the fall cycle of O’Neal Invests.
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Abstract artwork with yellow, black, white, green, pink, orange, and red
January 25, 2024

ArtBLINK Gala returns for 39th year to support cancer research

The advisory board of the O’Neal Comprehensive Cancer Center at the University of Alabama at Birmingham will host its 39th annual ArtBLINK Gala on Saturday, Feb. 3, at 6:30 p.m. in the UAB Kirklin Clinic.
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January 25, 2024

O’Neal Comprehensive Cancer Center announces recipients of cancer-related research grants through O’Neal Invests

The O’Neal Comprehensive Cancer Center at UAB is pleased to announce its fall 2023 O’Neal Invests grant awards.
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December 20, 2023

UAB Breast Cancer Team presents at the San Antonio Breast Cancer Symposium

UAB’s Breast Cancer Team presented at the San Antonio Breast Cancer Symposium (SABCS) December 5 through December 9, 2023.
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December 11, 2023

UAB cancer biology undergraduate student presents at the ASCO Quality Care Symposium

UAB cancer biology undergraduate student Emma Hendrix attended the ASCO Quality Care Symposium October 27, 2023, to present her research poster “Evaluating shared-decision making among women with metastatic breast cancer.” One detail made this opportunity uniquely special however: She presented her research with her grandfather, oncologist Patrick Daugherty, M.D., in attendance.
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Female nurse attending to an African American female patient
November 13, 2023

UAB works to improve immunotherapy in treating gynecologic cancers

Immunotherapy is a common type of treatment that uses the patient’s own immune system to fight cancer and other diseases. Gynecologic cancers are treated in different ways, but immunotherapy is becoming more common in treating cervical cancer, uterine (endometrial) cancer, and other cancers that start in women’s reproductive organs.
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November 3, 2023

Highlights from October cancer fundraising events

The O’Neal Comprehensive Cancer Center wants to thank everyone for their support and participation during October’s Breast Cancer Awareness Month. From Witches Rides to 5K runs, below are some photos highlighting events from around the greater Birmingham area.
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Collage of portraits of smiling diverse women
October 20, 2023

UAB launches WISDOM study and seeks participants in breast cancer screening study

The O’Neal Comprehensive Cancer Center is recruiting women in Alabama to join the WISDOM study, or Women Informed to Screen Depending On Measures of risk, which is an innovative national research study designed to test a personalized approach to breast cancer screening and prevention.
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October 20, 2023

O’Neal Comprehensive Cancer Center hosts 23rd annual Research Retreat at Regions Field

The O’Neal Comprehensive Cancer Center at UAB hosted its 23rd annual Research Retreat Friday, October 13, at Regions Field. More than 350 attendees joined the day-long event.
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August 23, 2023

O’Neal Comprehensive Cancer Center announces recipients of cancer-related research grants through O’Neal Invests

The O’Neal Comprehensive Cancer Center at UAB is pleased to announce its latest O’Neal Invests grant awards. O’Neal Invests funds UAB investigators initiating new cancer-related projects to do key preliminary work to enable competitive extramural applications. Applications for the seventh grant cycle were submitted in Spring 2023.
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August 23, 2023

Mike Slive Foundation funds cancer-related research grant through O’Neal Invests

The O’Neal Comprehensive Cancer Center at UAB is pleased to announce that the Mike Slive Foundation has generously funded a Pre-R01 grant through the spring cycle of O’Neal Invests.
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August 23, 2023

BCRFA funds cancer-related research grant through O’Neal Invests

The O’Neal Comprehensive Cancer Center at UAB is pleased to announce that the Breast Cancer Resesarch Foundation of Alabama (BCRFA) has generously funded a Pre-R01 grant through the spring cycle of O’Neal Invests.
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Office, conference and break areas cover around 4,000 square feet.
August 11, 2023

Cutting-edge cancer research lab opens operations at Pepper Place

Birmingham’s Pepper Place has a striking new addition to its teeming farmers’ market and noted food offerings — a multimillion-dollar cancer research laboratory. 
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UAB Proton Therapy Center ProBeam Proton Therapy System, 2020
July 19, 2023

New cancer therapy being studied at UAB could one day offer complete radiation treatment in milliseconds

A full course of radiation therapy in milliseconds rather than weeks: That’s the promise of flash therapy.
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Caucasian female holding up a teal ribbon for Ovarian Cancer
July 14, 2023

One-of-a-kind Alabama ovarian cancer car tags raise nearly $1.7 million for ovarian cancer research at UAB

Alabama is one of three states currently offering an ovarian cancer car tag — and it is changing the future of ovarian cancer research. Since the tag’s inception, proceeds from each ovarian cancer car tag purchased have gone directly to the University of Alabama at Birmingham’s Division of Gynecologic Oncology to support ovarian cancer research.
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Researcher works in lab
June 29, 2023

American Society of Clinical Oncology Report

UAB was well represented at one of the signature oncology conferences this year, ASCO, held in Chicago, Illinois, from May 31–June 4.
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Markus Bredel, M.D. (Professor, Radiation Oncology)
June 21, 2023

Bredel findings address understanding of diffuse gliomas

Markus Bredel, M.D., Ph.D., is lead author on “Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas” in Cell Reports Medicine (2023). This groundbreaking discovery not only marks a significant milestone in our understanding of diffuse gliomas but also paves the way for improved predictions of disease outcomes and the development of targeted treatment approaches.
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Headshots of the five O'Neal Invests Fall 2022 Awardees
March 1, 2023

O’Neal Comprehensive Cancer Center awards $530,000 in cancer-related research grants through O’Neal Invests

The O’Neal Comprehensive Cancer Center at UAB recently awarded six projects a total of $530,000 in research grants through O'Neal Invests. The O’Neal Invests program funds UAB investigators initiating new cancer-related projects to do key, preliminary work in order to enable competitive R01 applications.
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